Estimation of the basic reproduction number (R0) for the novel coronavirus disease in Sri Lanka
| dc.contributor.author | Samath Dharmaratne | |
| dc.contributor.author | Supun Sudaraka | |
| dc.contributor.author | Ishanya Abeyagunawardena | |
| dc.contributor.author | Kasun Manchanayake | |
| dc.contributor.author | Mahen Kothalawala | |
| dc.contributor.author | Wasantha Gunathunga | |
| dc.date.accessioned | 2024-04-24T04:40:01Z | |
| dc.date.available | 2024-04-24T04:40:01Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Background: The basic reproduction number (R0) is the number of cases directly caused by an infected individual throughout his infectious period. R0 is used to determine the ability of a disease to spread within a given population. The reproduction number (R) represents the transmissibility of a disease. Objectives: We aimed to calculate the R0 of Coronavirus disease-2019 (COVID-19) in Sri Lanka and to describe the variation of R, with its implications to the prevention and control of the disease. Methods: Data was obtained from daily situation reports of the Epidemiology Unit, Sri Lanka and a compartmental model was used to calculate the R0 using estimated model parameters. This value was corroborated by using two more methods, the exponential growth rate method and maximum likelihood method to obtain a better estimate for R0. The variation of R was illustrated using a Bayesian statistical inference-based method. Results: The R0 calculated by the first model was 1.02 [confidence interval (CI) of 0.75-1.29] with a root mean squared error of 7.72. The exponential growth rate method and the maximum likelihood estimation method yielded an R0 of 0.93 (CI of 0.77-1.10) and a R0 of 1.23 (CI of 0.94-1.57) respectively. The variation of R ranged from 0.69 to 2.20. Conclusion: The estimated R0 for COVID-19 in Sri Lanka, calculated by three different methods, falls between 0.93 and 1.23, and the transmissibility R has reduced, indicating that measures implemented have achieved a good control of disease. | |
| dc.identifier.citation | Dharmaratne S, Sudaraka S, Abeyagunawardena I, Manchanayake K, Kothalawala M, Gunathunga W. Estimation of the basic reproduction number (R0) for the novel coronavirus disease in Sri Lanka. Virology Journal. 2020 Dec;17:1-7. | |
| dc.identifier.uri | https://ir.lib.pdn.ac.lk/handle/20.500.14444/361 | |
| dc.publisher | Elsevier | |
| dc.title | Estimation of the basic reproduction number (R0) for the novel coronavirus disease in Sri Lanka | |
| dc.type | Article |