Bone formation and remodeling pattern in the mandible
Date
2000-12-16
Authors
Arambaawtta, A. K. S.
Peiris, H. R. D.
Nanayakkara, D.
Journal Title
Journal ISSN
Volume Title
Publisher
University of Peradeniya, Peradeniya
Abstract
The development of the mandible occurs mainly by intramembranous ossification. However, its subsequent growth is brought about by the secondary cartilages that appear in the heads of the condyles. The present study was carried out to identify the bone formation and remodeling pattern in the mandible,
and to establish the rate of bone formation at different sites in the mandible.
Five male and five female Sprague Dawley rats receiving a normal diet were mated. From the day of mating, a bone marker, Calcein (flurescein methylene iminodiacetic acid- 30mglkg body weight), was injected intraperitoneally to the female rats at weekly intervals. This was continued on the new born rats up to seven weeks and the rats were sacrificed.
Ground sections were prepared from the condyle and the base of the mandible. The observations under fluorescent microscopy revealed that the pattern of bone formation differed in the condyle and the base of the mandible.
Clear fluorescent lines arranged in an organized manner were seen in the base. This arrangement was absent in the condyle and the fluorescent material was deposited in a random manner. In the growth cartilage of the condyle the proliferating cartilage cells are not arranged in columns as in the growth cartilage of a long bone. Therefore, the growth at the condylar head is multidirectional and fluorescent lines are not seen.
The distance between fluorescent lines were measured using a calibrated ocular grid at the buccal alveolar bone, lingual alveolar bone, and the basal bone of the mandible. The mean values of bone formation obtained for these sites were 10.00 ± 9.16 11m, 42.8S± 00 11mand 2186± 10.39 11mrespectively. 195
Description
Keywords
Medicine , Bone formation Remodeling pattern
Citation
Proceedings and Abstract of the Annual Research Sessions, December 16, 2000, University of Peradeniya, Sri Lanka pp 195