Insecticidal Activity of Arylalkenes
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Date
2001-11-16
Authors
Priyadarshani, A. M. A.
Kumar, V.
Weerasekera, N.
Journal Title
Journal ISSN
Volume Title
Publisher
University of Peradeniya, Peradeniya, Sri Lanka
Abstract
Previous studies of Zingiber purpureum had shown the presence of an arylalkene, (E)- 1-(3' ,4' -dimethoxyphenyl)butadiene which was active against Aedes aegypti with LC50 of 6.5 ppm and against the bruchid, Callosobruchus maculatus with LC50 of 2mg1. The compound also showed oviposition deterrent and ovicidal effects against the bruchid.
The arylalkene was however unstable when exposed to light and air. Structurally related compounds were therefore synthesized in order to study the structure-activity relationship to obtain stable arylalkenes with the same or enhanced activity.
Arylalkenes were synthesized using the Wittig reaction. Aromatic aldehydes substituted with hydroxy and methoxy groups at different positions on the aromatic ring were reacted with Witting reagents of different lengths (1 to 4 carbons).
Para methoxy substituted arylalkenes were generally found to have strong insecticidal activity against Callosobruchus maculatus in the residual film bioassay. In the seed treatment bioassay, these compounds showed oviposition deterrent and ovicidal effects against the bruchid.
However the result against Aedes aegypti did not show any consistent pattern in the relationship between structure and activity.
Description
Keywords
Science , Inseticidal , Arylalkenes
Citation
Proceedings & abstracts of the Annual Research Sessions 2001,University of Peradeniya, Peradeniya, Sri Lanka,pp.150