The relationship of central obesity and thyroid, steroid and sex hormones
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Date
1998-11-07
Authors
Ariyasinghe, K. S. N.
Mendis, Shanthi
Udugama, C.
Thattil, R. O.
Gamini, G. A. B.
Journal Title
Journal ISSN
Volume Title
Publisher
University of Peradeniya
Abstract
Central Obesity is the deposition of excess fat in the central parts of the body. It is associated with a higher risk of cardiovascular disease. Pathogenesis of central obesityinclude metabolic, psychological, genetic and endocrine factors. The objective of this study was to investigate the influence of thyroxine, cortisol and progesterone on the development of central obesity.
· Two hundred and ninety two subjects (177 females and 115 males) were ·randomly selected from the electoral lists in the following manner. Of the two ·divisional secretariat divisions in the Kandy district, the Yatinuwara divisional ·secretariat division was selected. Out of95 gramasevaka divisions in the Yatinuwara ·division 6 gramasevaka divisions were randomly selected. The age range was 16-82 yearsfor males and 16-77 years for females. The anthropometric measurements availablefor measuring central obesity are skin fold thickness measurements and waist hip .circumferenceratio. The anthropometric measurements used in our study for assessing central obesity was the waist hip ratio. Waist circumference was measured at the levelof the naval, and hip circumference was measured at the level of the greater ."trochanters. Measurement of thyroxine, cortisol and progesterone were done by radio-immuno assay.
Correlation between waist hip ratio and serum thyroxine, progesterone and rtisol was r = -0.039, r = -0.349 and r = - 0.379 respectively for males and r = -0.112, II: _ 0.159, r = -0.153 respectively for females. In multiple regression analysis cortisol .md progesterone were significant inverse predictors of the waist hip ratio in men. standardised coefficient -0.282 and -0.239 respectively), but not in women. Serum thyroxine was not a predictor of central obesity in either sex
Description
Keywords
Thyroid , Obesity , Hormones , Health Sciences
Citation
Proceedings & Abstracts of the Annual Research Sessions,1998,University of Peradeniya, peradeniya, Sri Lanka, pp 50