Antimicrobial Activity of Some Sri Lankan Rubiaceae and Meliaceae
| dc.contributor.author | Jayasinghe, U. L. B. | |
| dc.contributor.author | Jayasooriya, C. P. | |
| dc.contributor.author | Bandara, B. M. R. | |
| dc.contributor.author | Ekanayake, S. P. | |
| dc.contributor.author | Merlini, L. | |
| dc.contributor.author | Assante, G | |
| dc.date.accessioned | 2024-11-29T08:24:47Z | |
| dc.date.available | 2024-11-29T08:24:47Z | |
| dc.date.issued | 2001-11-16 | |
| dc.description.abstract | Continuing our work on biologically active compounds from Sri Lankan plants we have now screened 94 solvent extracts (n-hexane, dichloromethane and methanol) obtained from leaves, bark and stem of thirteen Rubiaceae species (Benkara malabarica, Canthium coromandelicum, Canthium dicoccum, Haldina cordifolia, Ixora calycina, Morinda tinctoria, Mussaendafrondosa, Psychotria gardneri, Psychotria nigra, Psycho tria stenophylla, Saprosma foetens, Tarenna asiatica and Wendlandia bicuspidatay and two Meliaceae species (Aglia congylos and Munronia pumilia) for antibacterial activity against Escherichia coli (Ec), Micrococcus luteus (Ml), Bacillus subtilis (Bs) and Bacillus cereus (Bc) and antifungal activity against Saccharomyces cerevisiae (Se), Ustilago maydis (Um) and Aspergillus niger (An). Screening for antimicrobial activity was carried out using the disc diffusion method. The media used for culturing bacteria, fungi and yeast like fungi were nutrient agar, Czapek agar and glucose yeast agar, respectively. The plants M.tinctoria, M.frondosa, P. gardneri and P. stenophylla showed antimicrobial activity against at least five of the seven microbes examined: M. tinetoria (leaves) - hexane extract against Ec, Bs, Be and An, and dichloromethane extract against Sc, Ec and Be; M tinetoria(bark) - dichloromethane extract against Se, Ec, Bs and An, and methanol extract against MI and Be; M frondosa (leaves) - dichloromethane extract against Sc, Ec, Bs and Be, and methanol extract against Bs; M frondosa (bark) - hexane extract against Sc, Um, Ml and Be, dichloromethane extract against Se, MI and Be, and methanol extract against Ec and Bs; P. gardneri (leaves) - dichloromethane extract against An,. and methanol extract against Sc, £C, Ml and Be; P. gardneri (bark) - hexane extract against An, dichloromethane extract against Se and Bs, and methanol extract against Ec, MI, Bs and Be; P. stenophylla (leaves) - dichloromethane extract against Ec; P. stenophylla (bark) - dichloromethane extract against Um, £C, MI, Bs, Be and An and methanol extract against MI. The following extracts were found to be inactive: A. congylos (leaves - methanol), B. malabarica (leaves - hexane), C. coromandelicum (leaves - hexane), H. eordifolia (leaves -hexane, bark - hexane and methanol), I. calycina (bark - hexane), M tinetoria (leaves-methanol, bark - hexane), M. frondosa (leaves - hexane), M puma/ia (leaves - hexane, dichloromethane and methanol), P. gardneri (leaves - hexane), P. nigra (leaves - hexane and dichloromethane), P. stenophylla (leaves - hexane and methanol, bark - hexane), S. foetens (bark - hexane), T asiatica (bark - hexane), W bicuspidata (leaves - methanol, bark - methanol). | |
| dc.description.sponsorship | Financial support from the Italy-Sri Lanka research collaboration program is gratefully acknowledged. | |
| dc.identifier.citation | Proceedings & abstracts of the Annual Research Sessions 2001,University of Peradeniya, Peradeniya, Sri Lanka,pp.110 | |
| dc.identifier.issn | 955-583-063-0 | |
| dc.identifier.uri | https://ir.lib.pdn.ac.lk/handle/20.500.14444/4284 | |
| dc.language.iso | en | |
| dc.publisher | University of Peradeniya, Peradeniya, Sri Lanka | |
| dc.subject | Antimicrobial | |
| dc.subject | Science | |
| dc.subject | Activity | |
| dc.subject | Rubiaceae | |
| dc.subject | Meliaceae | |
| dc.title | Antimicrobial Activity of Some Sri Lankan Rubiaceae and Meliaceae | |
| dc.type | Article |